Dr. Carlos A. Morillo

Board Member of WSA

Dr. Carlos A. Morillo is a Cardiologist and Electrophysiologist and currently a Full Professor in the Department of Cardiac Sciences, and a Senior Visiting Scientist within the Molecular and Novel Arrhythmia Mechanisms group at the Centro Nacional de Investigaciones Clinicas (CNIC), in Madrid, Spain. Dr. Morillo served as the Section Chief Cardiology Division at the Libin Cardiovascular Institute, and Zone Head Cardiology, Alberta Health Services, from 2016-2022.

Dr. Morillo was the Director of the Hamilton Atrial Fibrillation Reference Centre, Director of the Syncope Autonomic Disorder Unit at McMaster University (2002-2014), and the past Director of the Arrhythmia & Pacing Services from 2002-2012, and Cardiac Electrophysiology & Pacing fellowship program director at McMaster University. Dr. Morillo received his MD and Internal Medicine and Cardiology certifications from the Pontificia Universidad Javeriana, and Universidad Militar Nueva Granada, respectively in Bogota, Colombia. He trained as a Cardiologist and Cardiac electrophysiologist at the University of Western Ontario in London, Ontario Canada under the mentorship of Professor George Klein; he performed a post- doctoral fellowship sponsored by the Heart & Stroke Foundation of Canada in Cardiovascular Autonomic Physiology, under the mentorship of Professor Dwain Eckberg, and Kenneth Ellenbogen at the Medical College of Virginia, Virginia Commonwealth University, where he was on staff for 5 years.

His main research interests include the development of clinical trials in the area of cardiac arrhythmias, syncope and treatment of Chagas Disease. Similarly, he has performed research in cardiac autonomic regulation, sympathetic nerve traffic and baroreflex modulation in different disease stages such as Sudden Cardiac death, stroke, neurally mediated reflex syncope and Chagas cardiomyopathy. Dr. Morillo has a long-lasting interest in developing new therapeutic approaches for the treatment of atrial fibrillation and autonomic disorders. Dr. Morillo has published more than 400 articles in peered reviewed journals, over 380 abstracts and 35 book chapters in well know Cardiology textbooks and has published in most of the mayor journals such as New England Journal of Medicine, JAMA, JACC, Circulation, European Heart Journal, Stroke, Journal of Cardiac Electrophysiology, Annals of Internal Medicine. Dr. Morillo has large experience with neurally mediated orthostatic intolerance symptoms and has participated in most of the landmark clinical trials in this condition. He also developed the first chronic AF experimental model and was the first to document the potential of cryoablation of the pulmonary vein region as a strategy to treat AF experimentally. He is currently focused on the development and implementation of clinical networks that will develop the necessary infrastructure to conduct clinical trials of neglected diseases such as Chagas and Rheumatic Heart Disease; he has also developed clinical pathways to improve management and assessment of patients with atrial fibrillation and syncope that present to the emergency department. Dr. Morillo holds or has held grants from CIHR, NIH, CaNET, COLCIENCIAS, TDR/WHO, Fundación Occident, and industry. Dr. Morillo is the principal investigator of the largest clinical trial in Chagas disease ever conducted (BENEFIT Trial) and is testing new therapeutic agents for the management of this neglected disease (STOP-CHAGAS, PARACHUTE-HF). Dr. Morillo is a member of the steering committee of many landmark Clinical trials including INTERHEART, ORIGIN, CURRENT, OASIS, BENEFIT, ASSERT, ACTIVE, CRYSTAL-AF, STOP-CHAGAS, POST, RELY, ELIMINATE-AF, RAAFT-2, EARLY-AF, AWARE 1&2, STAR-AF 1-3, VENUS to mention a few, and has participated as an investigator and a member of the Adjudications committees of trials such as ORIGIN, RELY, BENEFIT, AVERROES, RAAFT-2, SIMPLE and many other landmark clinical trials. Dr. Morillo was the Editor-in-Chief of the Revista Iberoamericana de Arritmologia and is a member of several Editorial Boards including the Cochrane Meta-Analysis Heart Group, Clinical Autonomic Research, EUROPACE, Heart Rhythm Journal, Revista Colombiana de Cardiologia, REBLAMPA, and served in the editorial boards of JCE, EUROPACE, HRJ, JICE,and other journals. Dr. Morillo is an internationally renowned lecturer and teacher. He has received many accolades nationally and internationally and awarded as one of the 10 most influential Hispanic-Canadians in 2010.

He has also been very actively involved with Cardiology Societies in North and Latin America including being a past board member of the Inter-American Heart Foundation, the American Autonomic Society and a past Vice-President of the Inter-American Cardiology Society, and served as the Heart Rhythm Society Ambassador for Latin America and a past member of the Scientific Meeting Planning Committee for the Heart Rhythm Society. He served as lead for the Heart Rhythm Disorder Planning program for the World Congress of Cardiology (Mexico, 2016) and Chair of the AF Roadmap for the World Heart Federation. He is also a member of the IASC, WHF Chagas committees, as well as an Advisory Board member for Drug for Neglected Diseases and a member of the Scientific Advisory Committee of the Infectious Disease Data Observatory (Oxford University), Chagas Platform. Dr. Morillo has had an active role in many specialty and Subspecialty Society Boards both nationally and internationally and has held all type of board positions such as Secretary, Treasurer, Vice-President and President. He was the Founding President of the Colombian Heart Foundation, a founding Board Member of the Canadian Heart Rhythm Society and former President of SOLAECE today Latin American Heart Rhythm Society (LAHRS), and currently a board member of the World Society of Arrhythmias (WSA). Dr. Morillo has trained over 40 fellows from 4 continents and also has experience organizing educational cardiology meetings focusing on translation of evidenced based medicine into clinical practice within Latin America and Chaired the McMaster University, Cardiology Update Annual Symposium for 6 continuous years. Dr. Morillo is currently developing novel antiarrhythmics and working with the groups of Professor Jalife and Dr. Filgueras on AF epigenetics and mechanisms of progression of AF.

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